The receiver operating characteristic (ROC) curve is commonly used to evaluate the accuracy of a diagnostic test for classifying observations into two groups.We propose two novel tuning parameters for estimating the ROC curve via Bernstein polynomial smoothing of the empirical ROC curve.The Plasma Consumable new estimator is very easy to implement
Abstract One of the most important questions in evolutionary biology is how the spatial distribution of species is limited.Asymmetric gene flow from core populations is suggested to increase the number of poorly adapted immigrants in the populations at the range edge.Genetic load due to migration, i.e., migration load, should prevent adaptation to
Lung cancer is the leading cause of cancer deaths worldwide.Clinically, the treatment of non-small cell lung cancer (NSCLC) can be improved by the early detection and risk screening among population.To meet this need, here we describe the application of extensive peptide level fractionation coupled with label free quantitative proteomics for the di
Abstract The main advantages of microneedles are precise drug delivery through human skin, minimal tissue damage and painlessness.We conducted structural analysis and skin puncture studies of hollow microneedles using ANSYS for three materials: Hafnium Dioxide (HfO2), Capacitor Polyglycolic acid (PGA) and Polylactic acid (PLA).Firstly, we selected